Outcome
    Limited

    L-Citrulline for Sexual Stamina

    Citrulline supports blood flow and general exercise endurance, with weak direct sexual stamina data.

    Overview

    Citrulline supports blood flow and general exercise endurance, with weak direct sexual stamina data.

    Verdict

    Insufficient evidence

    How It Works

    Nitric oxide-mediated vasodilation improves perfusion and reduces fatigue accumulation.

    Dosing & Protocol

    Typical dose

    Recommended dose
    1.5-6 g L-citrulline daily (extrapolated from ED studies)
    Expected timeframe
    Not established

    Protocol

    dose
    1.5-6 g/day (studied for erectile hardness, not stamina)
    form
    L-citrulline
    timing
    Daily
    duration
    Not established

    Evidence

    What the studies say

    Exercise trials show improved endurance and reduced soreness. Sexual stamina has not been directly studied as an outcome.

    Efficacy of L-citrulline oral supplementation in mild erectile dysfunction

    Score: 5/10
    2011
    crossover
    n=24

    Cormio L, De Siati M, Lorusso F +4 more

    Erection hardness improved from mild dysfunction to normal in 50% of citrulline patients versus 8.3% on placebo

    View source

    Oral L-citrulline supplementation improves erection hardness in men with mild erectile dysfunction

    Score: 5/10
    2011
    rct
    n=24

    Cormio L, De Siati M, Lorusso F +4 more

    Erection hardness score improved to normal in 50% of men on L-citrulline versus 8.3% on placebo.

    View source

    Safety

    Caveats

    INSUFFICIENT verdict: studied doses target erectile hardness, not stamina; state the studied dose and the absence of direct evidence rather than following an invented regimen. Nitrate/PDE5 interaction applies. Pregnancy data lacking — avoid.

    Less likely to help if

    Unknown

    Medical Disclaimer

    The information provided on this website is for educational and informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any supplement regimen.

    Individual results may vary. The statements on this website have not been evaluated by the Food and Drug Administration. Products and information are not intended to diagnose, treat, cure, or prevent any disease.