Outcome
    Moderate Evidence

    Biotin (Vitamin B7) for Wrinkle Reduction

    Biotin does nothing for wrinkles and interferes with laboratory tests.

    Overview

    Biotin does nothing for wrinkles and interferes with laboratory tests.

    Verdict

    Not supported

    How It Works

    Cofactor in fatty acid synthesis; deficiency affects skin and hair.

    Dosing & Protocol

    Typical dose

    Recommended dose
    Not recommended
    Expected timeframe
    n/a

    Protocol

    studied dose
    5,000-10,000 mcg/day marketed dose, with no wrinkle endpoint ever assessed in a controlled trial
    evidence note
    Verdict is no - no evidence for wrinkles or skin ageing in people who are not deficient
    what happened
    No study has measured wrinkle depth, photoageing or skin ageing markers with biotin. High doses do cause clinically significant interference with laboratory tests
    critical lab warning
    Stop biotin 3 days before any blood test
    what actually has evidence
    Daily broad-spectrum sunscreen is the single most effective anti-ageing intervention, followed by topical retinoids; collagen peptides have modest supporting data

    Evidence

    What the studies say

    No evidence supports biotin for wrinkles or skin ageing in people who are not deficient. High doses cause clinically significant interference with troponin and thyroid assays.

    No studies are yet linked to both Biotin (Vitamin B7) and Wrinkle Reduction.

    Safety

    Caveats

    Interferes with troponin and thyroid immunoassays, risking misdiagnosis.

    Less likely to help if

    Everyone - no wrinkle benefit has been shown in any population.

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    Individual results may vary. The statements on this website have not been evaluated by the Food and Drug Administration. Products and information are not intended to diagnose, treat, cure, or prevent any disease.