Resveratrol for Telomere Protection
Resveratrol's telomere claims come from cell culture, not people.
Overview
Verdict
How It Works
Dosing & Protocol
Typical dose
- Recommended dose
- Not recommended for this purpose
- Expected timeframe
- n/a
Protocol
- form
- Trans-resveratrol was used at 150-1,000 mg/day in trials with other endpoints
- duration
- Not applicable
- co factor
- Evidence is insufficient. Cell culture work shows resveratrol can influence telomerase activity, though in both directions depending on cell type and concentration - it has been reported to activate telomerase in endothelial cells and to inhibit it in cancer cells, the latter being part of its proposed anticancer mechanism. No human trial has measured leukocyte telomere length or telomerase activity before and after resveratrol supplementation. Telomere length is also a problematic target: it is highly variable between individuals and assays, its shortening is a marker of replicative history rather than a modifiable cause of aging, and telomerase activation carries theoretical cancer risk.
- titration
- Not applicable
- starting dose
- Not established. No human trial has measured telomere length or telomerase activity after resveratrol
Evidence
What the studies say
No studies are yet linked to both Resveratrol and Telomere Protection.
Safety
Caveats
The underlying sirtuin activation premise did not survive scrutiny.
Less likely to help if
Medical Disclaimer
The information provided on this website is for educational and informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any supplement regimen.
Individual results may vary. The statements on this website have not been evaluated by the Food and Drug Administration. Products and information are not intended to diagnose, treat, cure, or prevent any disease.