Outcome
    Limited

    L-Glutamine for Wound Healing

    Glutamine matters in burns and critical illness rather than routine wounds.

    Overview

    Glutamine matters in burns and critical illness rather than routine wounds.

    Verdict

    Insufficient evidence

    How It Works

    Fuel for enterocytes and immune cells during catabolic stress.

    Dosing & Protocol

    Typical dose

    Recommended dose
    Only in catabolic states, clinician-guided
    Expected timeframe
    2-4 weeks

    Protocol

    form
    Not applicable
    duration
    Not applicable
    co factor
    Evidence is insufficient. Glutamine supports proliferating fibroblasts and immune cells and is a nitrogen donor for collagen precursors, and it becomes conditionally essential in severe catabolic states, so burns and major trauma are where it has been studied - at 0.3-0.5 g/kg/day, sometimes with arginine and other immunonutrients. Results are inconsistent: some burn studies report faster wound closure and fewer infections, others show nothing, and because glutamine is usually given as part of a combined immunonutrition formula, its individual contribution cannot be separated. There is no evidence for glutamine in ordinary wound healing in well-nourished people.
    titration
    Not applicable
    starting dose
    Not applicable as an established treatment outside supervised clinical nutrition

    Evidence

    What the studies say

    Benefits are documented in burns and critical illness. Routine wound healing in well-nourished people shows no advantage.

    No studies are yet linked to both L-Glutamine and Wound Healing.

    Safety

    Caveats

    No benefit in ordinary wounds. Avoid in liver and kidney disease.

    Less likely to help if

    Well-nourished people with ordinary wounds, where glutamine is not limiting.

    Medical Disclaimer

    The information provided on this website is for educational and informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any supplement regimen.

    Individual results may vary. The statements on this website have not been evaluated by the Food and Drug Administration. Products and information are not intended to diagnose, treat, cure, or prevent any disease.