Apigenin for Improved Sleep Quality
Isolated apigenin has not been tested for sleep in humans; the reputation rests on chamomile.
Overview
Verdict
How It Works
Dosing & Protocol
Typical dose
- Recommended dose
- No validated dose - purified apigenin has never been tested for sleep
- Expected timeframe
- Not established
Protocol
- studied dose
- Chamomile extract at 270-1500 mg/day, containing only small and variable amounts of apigenin
- evidence note
- Verdict is insufficient - no randomised trial of purified apigenin for sleep exists
- what happened
- Chamomile trials produced small and inconsistent sleep-quality changes, and the active constituent was never isolated, so nothing can be attributed to apigenin itself
- better first choices
- Magnesium glycinate and melatonin have direct randomised sleep data
- if you still trial it
- Use a standardised chamomile extract rather than isolated apigenin, keep it to a 2-4 week trial, and score sleep quality weekly
Evidence
What the studies say
No studies are yet linked to both Apigenin and Improved Sleep Quality.
Safety
Caveats
Chamomile can trigger allergic reactions in people sensitive to ragweed, daisies or chrysanthemums. It may add to the effect of sedatives and anticoagulants. Apigenin content varies enormously between preparations, so dose is unknowable in practice. Avoid in pregnancy.
Less likely to help if
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Individual results may vary. The statements on this website have not been evaluated by the Food and Drug Administration. Products and information are not intended to diagnose, treat, cure, or prevent any disease.