Magnesium, Calcium, Potassium, Sodium, Phosphorus, Selenium, Zinc, and Chromium Levels in Alcohol Use Disorder: A Review
Baj J
Published in Journal of Clinical Medicine
Methodology
Literature review of studies reporting serum, plasma or tissue levels of magnesium, calcium, potassium, sodium, phosphorus, selenium, zinc and chromium in patients with alcohol use disorder.
Key Findings
Review of mineral status in alcohol use disorder found consistently low magnesium, zinc and selenium levels and frequently disturbed calcium, potassium, sodium and phosphate balance, driven by poor intake, gastrointestinal losses, renal wasting and liver dysfunction; deficiencies were linked to withdrawal severity, neuropathy, arrhythmia risk and refeeding complications.
Conclusions
Mineral deficiencies - particularly magnesium and zinc - are common in alcohol use disorder and warrant assessment and correction as part of treatment, though evidence that supplementation improves drinking outcomes is limited.
Limitations
Narrative/systematic review of heterogeneous observational studies with varied assay methods and populations; no pooled estimates; few interventional trials; confounding by nutrition, liver disease and comorbidity.
Supplements Studied
Such knowledge helps to understand the mechanisms of chronic alcohol-use disorder and to progress and prevent withdrawal effects, also improving treatment strategies.
Such knowledge helps to understand the mechanisms of chronic alcohol-use disorder and to progress and prevent withdrawal effects, also improving treatment strategies.
Review of mineral status in alcohol use disorder found consistently low magnesium, zinc and selenium levels and frequently disturbed calcium, potassium, sodium and phosphate balance, driven by poor intake, gastrointestinal losses, renal wasting and liver dysfunction; deficiencies were linked to withdrawal severity, neuropathy, arrhythmia risk and refeeding complications.
Review of mineral status in alcohol use disorder found consistently low magnesium, zinc and selenium levels and frequently disturbed calcium, potassium, sodium and phosphate balance, driven by poor intake, gastrointestinal losses, renal wasting and liver dysfunction; deficiencies were linked to withdrawal severity, neuropathy, arrhythmia risk and refeeding complications.
Review of mineral status in alcohol use disorder found consistently low magnesium, zinc and selenium levels and frequently disturbed calcium, potassium, sodium and phosphate balance, driven by poor intake, gastrointestinal losses, renal wasting and liver dysfunction; deficiencies were linked to withdrawal severity, neuropathy, arrhythmia risk and refeeding complications.
Review of mineral status in alcohol use disorder found consistently low magnesium, zinc and selenium levels and frequently disturbed calcium, potassium, sodium and phosphate balance, driven by poor intake, gastrointestinal losses, renal wasting and liver dysfunction; deficiencies were linked to withdrawal severity, neuropathy, arrhythmia risk and refeeding complications.
Related Health Concerns
Study Details
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Disclosures
Funding
University research funding (Medical University of Lublin)
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