meta_analysis
    2011
    High Quality

    The effect of grape seed extract on cardiovascular risk markers: a meta-analysis of randomized controlled trials

    Feringa HH, Laskey DA, Dickson JE, Coleman CI

    Published in Journal of the American Dietetic Association

    Methodology

    Meta-analysis of 9 randomised controlled trials of grape seed extract on blood pressure, heart rate and lipids

    Key Findings

    Grape seed extract significantly lowered systolic blood pressure by 1.54 mmHg and heart rate by 1.42 bpm, with no significant effect on lipids or C-reactive protein.

    Conclusions

    Grape seed extract produces small blood pressure reductions but does not improve lipid profiles.

    Limitations

    Small trials with heterogeneous preparations and doses.

    Supplements Studied

    Grape seed extract significantly lowered systolic blood pressure and heart rate but had no effect on lipid levels or C-reactive protein.

    Outcomes Measured

    Grape seed extract significantly lowered systolic blood pressure and heart rate.

    Grape seed extract significantly lowered systolic blood pressure by 1.54 mmHg and heart rate by 1.42 bpm, with no significant effect on lipids or C-reactive protein.

    Related Health Concerns

    Study Details

    Year:2011
    Sample Size:390
    Duration:8 weeks
    Quality Score:8/10

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