systematic_review
    2017
    High Quality

    Probiotics for vulvovaginal candidiasis in non-pregnant women

    Xie HY, Feng D, Wei DM

    Published in Cochrane Database of Systematic Reviews

    Methodology

    Cochrane review of 10 RCTs of probiotics as adjunct to conventional antifungal treatment for vulvovaginal candidiasis.

    Key Findings

    Probiotics as adjuncts may increase short-term clinical and mycological cure and lower one-month relapse, but all evidence was low or very low certainty.

    Conclusions

    Probiotics are a plausible adjunct to antifungals, not a standalone treatment for candida overgrowth.

    Limitations

    Low certainty; heterogeneous strains and routes; short follow-up.

    Supplements Studied

    Probiotics
    Probiotic

    Probiotics as adjuncts to antifungals may improve short-term cure and reduce one-month relapse of candidiasis.

    Probiotic adjuncts, including yeast and lactobacillus preparations, showed low-certainty benefit in candidiasis.

    Outcomes Measured

    Probiotic adjuncts improved short-term mycological cure in vulvovaginal candidiasis.

    There is insufficient high-quality evidence to support the use of probiotics for vulvovaginal candidiasis in non-pregnant women.

    To assess the effectiveness and safety of probiotics for the treatment of vulvovaginal candidiasis in non-pregnant women.

    Related Health Concerns

    Study Details

    Year:2017
    Sample Size:1,656
    Quality Score:8/10

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