Sleep Maintenance
Fewer nighttime awakenings and improved sleep continuity.
TL;DR
Staying asleep is a different problem from falling asleep. Melatonin barely helps maintenance; temperature, alcohol, late caffeine and sleep-restriction therapy matter far more.
Why It Matters
Sleep maintenance insomnia means frequent or prolonged night awakenings despite adequate opportunity. Common drivers include alcohol, which fragments the second half of the night as it metabolises, nocturia, pain, untreated sleep apnea, perimenopausal vasomotor symptoms, and conditioned hyperarousal. Cognitive behavioural therapy for insomnia is first-line and outperforms medication at long-term follow-up. Melatonin's trial evidence is mainly for sleep onset and circadian shifting, not maintenance, which is why it disappoints people who wake at 3am.
How to Measure
Biomarkers
Optimization Protocol
1) Keep the bedroom cool at 16-19C, since core temperature fall supports sleep continuity. 2) Cut alcohol, the most common and most reversible cause of second-half awakenings. 3) Follow a consistent wake time seven days a week, which stabilises circadian and homeostatic drive. 4) Use CBT-I techniques including stimulus control and sleep restriction, the first-line evidence-based treatment. 5) Stop caffeine 8-10 hours before bed given its long half-life. 6) Reduce evening fluid to limit nocturia, and get prostate symptoms assessed if relevant. 7) Block light fully and use a white noise source if the environment is disruptive. 8) Screen for sleep apnea, restless legs and perimenopause, which are frequently missed causes.
Lifestyle Levers
- •Cool bedroom 16-19C
- •Alcohol elimination
- •Fixed wake time
- •CBT-I and sleep restriction
- •Caffeine cutoff 8-10h
- •Evening fluid management
- •Full darkness
Supporting Supplements
Magnesium
Magnesium has modest sleep evidence, mostly in older adults and those with low intake.
Melatonin
Melatonin helps sleep onset and circadian timing far more than it helps staying asleep.
Glycine
Glycine has consistent small-trial evidence for sleep quality via core temperature lowering.
5-HTP
5-HTP has weak sleep evidence and meaningful interaction risk.
Ashwagandha
Ashwagandha improves sleep quality in trials, especially where stress drives the awakenings.
L-Theanine
L-theanine reduces pre-sleep arousal but has weak maintenance-specific evidence.
Supporting Research
Frequently Asked Questions
Typical Timeframe
Alcohol removal helps within days. CBT-I produces durable change in 4-8 weeks.
Research Summary
My Notes
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This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.