HDL Cholesterol Increase
More protective good cholesterol in the blood.
TL;DR
Raising HDL with drugs has repeatedly failed to reduce cardiac events, so HDL is a marker rather than a target. Exercise, weight loss and stopping smoking raise it in the way that actually correlates with benefit.
Why It Matters
Low HDL is associated with higher cardiovascular risk, but Mendelian randomisation and CETP inhibitor trials show raising it pharmacologically does not lower events. HDL function matters more than concentration.
How to Measure
Biomarkers
Optimization Protocol
Focus on the changes that improve overall lipid risk rather than HDL alone: regular aerobic exercise, losing excess visceral fat, stopping smoking, replacing refined carbohydrate with monounsaturated fat, and moderating alcohol. Track ApoB as the more actionable risk marker.
Supporting Supplements
Supporting Research
Frequently Asked Questions
Typical Timeframe
8-12 weeks
Research Summary
My Notes
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This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.