The efficacy of probiotics, prebiotics or synbiotics in scleroderma: A systematic review
Wach AA, Storman D, Więckowski K, Wojtaszek-Główka M
Published in Clinical Nutrition ESPEN
Methodology
Systematic review of randomized trials of probiotics, prebiotics or synbiotics in scleroderma, with outcomes including symptom scales, quality of life and SIBO eradication.
Key Findings
Trials were few and small; probiotic interventions did not demonstrate reliable SIBO eradication or symptom benefit in scleroderma.
Conclusions
Evidence is insufficient to recommend probiotics for SIBO in scleroderma.
Limitations
Very few RCTs; high risk of bias; indirect population.
Supplements Studied
The use of probiotic formulas brings benefit in treatment of various autoimmune diseases, but the evidence for scleroderma is still not exhaustive.
Related Health Concerns
Study Details
Access Study
Disclosures
Funding
Not reported
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.