systematic_review
    2017
    High Quality

    The putative effects of D-Aspartic acid on blood testosterone levels: A systematic review

    Roshanzamir F, Safavi SM

    Published in International Journal of Reproductive Biomedicine

    Methodology

    Systematic review of 23 animal and 4 human studies of D-aspartic acid and serum testosterone, searched to October 2015

    Key Findings

    Effects were species- and tissue-dependent in animals, while the small human literature showed inconsistent testosterone responses, including no effect in trained men.

    Conclusions

    Evidence does not support D-aspartic acid as a reliable testosterone booster in humans.

    Limitations

    Few human trials; small samples; heterogeneous doses and populations; no meta-analysis.

    Supplements Studied

    D-Aspartic Acid
    Amino Acid

    In vivo and in vitro animal studies revealed the effect of D-Asp depending on species, sex and organ-specific.

    Related Health Concerns

    Study Details

    Year:2017
    Quality Score:7/10

    Disclosures

    Funding

    Not reported

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.