rct
    2019
    High Quality

    Randomized clinical trial: the effect of probiotic Bacillus coagulans Unique IS2 vs. placebo on the symptoms management of irritable bowel syndrome in adults

    Madempudi RS, Ahire JJ, Neelamraju J, Tripathi A, Nanal S

    Published in Scientific Reports

    Methodology

    Randomized, double-blind, placebo-controlled 8-week trial of spore-forming B. coagulans Unique IS2 in adults with IBS.

    Key Findings

    Abdominal pain, bloating and stool frequency improved significantly versus placebo, with a higher rate of overall symptom relief.

    Conclusions

    Spore-based B. coagulans improved IBS symptoms in adults over 8 weeks.

    Limitations

    Single manufacturer-sponsored trial; single strain and dose.

    Supplements Studied

    Spore-based B. coagulans improved IBS symptoms in adults over 8 weeks.

    Abdominal pain, bloating and stool frequency improved significantly versus placebo, with a higher rate of overall symptom relief.

    Outcomes Measured

    Gut Microbiome Support
    Primary

    Spore-based B. coagulans improved IBS symptoms in adults over 8 weeks.

    Related Health Concerns

    IBS (Irritable Bowel Syndrome)
    Bloating & Gas

    Study Details

    Year:2019
    Sample Size:153
    Duration:8 weeks
    Quality Score:7/10

    Access Study

    View on DOIView on PubMedOriginal Source

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