Effects of citrus flavanone hesperidin extracts or purified hesperidin consumption on risk factors for cardiovascular disease: an updated meta-analysis of randomized controlled trials
Mas-Capdevila A, Teichenne J, Domenech-Coca C, Caimari A, Del Bas JM, Escote X, Crescenti A
Published in Current Developments in Nutrition
Methodology
Updated meta-analysis of randomised controlled trials of hesperidin extracts or purified hesperidin on cardiovascular risk markers
Key Findings
Hesperidin significantly reduced total cholesterol, LDL cholesterol and inflammatory markers, while effects on blood pressure and glycaemia were inconsistent.
Conclusions
Hesperidin modestly improves lipid and inflammatory markers; blood pressure benefits are unreliable.
Limitations
Heterogeneous doses, formulations and study populations.
Supplements Studied
Hesperidin significantly reduced total cholesterol, LDL cholesterol and inflammatory markers.
Outcomes Measured
Hesperidin significantly reduced LDL cholesterol and inflammatory markers.
Related Health Concerns
Study Details
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