meta_analysis
    2019
    High Quality

    Effect of probiotics on oral candidiasis: a systematic review and meta-analysis

    Mundula T, Ricci F, Barbetta B

    Published in Nutrients

    Methodology

    Meta-analysis of RCTs of probiotics on oral Candida colonisation and clinical candidiasis, largely in elderly and denture wearers.

    Key Findings

    Probiotics reduced Candida counts in the oral cavity (OR 0.24 for high colonisation) but clinical candidiasis endpoints were less consistent.

    Conclusions

    Probiotics reduce oral Candida load; clinical benefit is less clearly demonstrated.

    Limitations

    Mostly surrogate colonisation endpoints; varied strains and vehicles.

    Supplements Studied

    Probiotics
    Probiotic

    Probiotics reduced oral Candida colonisation versus control.

    Outcomes Measured

    Gut Microbiome Support

    Probiotics reduced oral Candida colonisation.

    Related Health Concerns

    Candida Overgrowth

    Study Details

    Year:2019
    Sample Size:1,092
    Quality Score:7/10

    Access Study

    View on DOIView on PubMedOriginal Source

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