Herbal Therapy Is Equivalent to Rifaximin for the Treatment of Small Intestinal Bacterial Overgrowth
Chedid V, Dhalla S, Clarke JO, Roland BC, Dunbar KB, Koh J, Justino E, Tomakin E, Mullin GE
Published in Global Advances in Health and Medicine
Methodology
Retrospective comparative study of berberine-containing herbal antimicrobial protocols versus rifaximin 1200 mg/day for four weeks in patients with breath-test-confirmed SIBO.
Key Findings
Normalisation of lactulose breath test occurred in 46% of the herbal therapy group versus 34% of the rifaximin group, with fewer adverse effects in the herbal arm.
Conclusions
Berberine-containing herbal antimicrobials are at least as effective as rifaximin for SIBO in this cohort.
Limitations
Retrospective, non-randomised, single-centre; multi-herb formulas prevent attribution to berberine alone.
Supplements Studied
Response rate for the herbal therapy group was 46% compared with 34% for the rifaximin group in patients with small intestinal bacterial overgrowth.
Outcomes Measured
Response rate for the herbal therapy group was 46% compared with 34% for the rifaximin group in patients with small intestinal bacterial overgrowth.
Herbal antimicrobials achieved breath-test normalisation in 46% of patients compared with 34% for rifaximin
Related Health Concerns
Study Details
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Disclosures
Funding
Institutional (Johns Hopkins) support
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