Probiotics for the prevention of antibiotic-associated diarrhea in adults: a meta-analysis of randomized placebo-controlled trials
Liao W, Chen C, Wen T, Zhao Q
Published in Journal of Clinical Gastroenterology
Methodology
Meta-analysis of 42 randomised placebo-controlled trials of probiotics, including Lactobacillus strains, for preventing antibiotic-associated diarrhoea in adults
Key Findings
Probiotics reduced the incidence of antibiotic-associated diarrhoea by roughly 40 percent, with benefit strongest when started early in the antibiotic course.
Conclusions
Lactobacillus-containing probiotics meaningfully reduce antibiotic-associated diarrhoea risk in adults.
Limitations
Strain heterogeneity; variable dosing and timing.
Supplements Studied
Probiotics reduced the incidence of antibiotic-associated diarrhoea by roughly 40 percent, with benefit strongest when started early in the antibiotic course.
Probiotics reduced the incidence of antibiotic-associated diarrhoea by roughly 40 percent, with benefit strongest when started early in the antibiotic course.
Outcomes Measured
Probiotics reduced the incidence of antibiotic-associated diarrhoea by roughly 40 percent, with benefit strongest when started early in the antibiotic course.
Related Health Concerns
Study Details
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