Serum levels of phosphorus, parathyroid hormone, and calcium and risks of death and cardiovascular disease in individuals with chronic kidney disease: a systematic review and meta-analysis
Palmer SC, Hayen A, Macaskill P, Pellegrini F, Craig JC, Elder GJ, Strippoli GFM
Published in JAMA
Methodology
Systematic review and meta-analysis of cohort studies of serum phosphorus, PTH and calcium with mortality in chronic kidney disease
Key Findings
Each 1 mg/dL increase in serum phosphorus was associated with an 18% higher risk of death in people with chronic kidney disease
Conclusions
Higher serum phosphorus predicts mortality in chronic kidney disease
Limitations
Observational studies only; does not establish that lowering phosphorus improves outcomes
Supplements Studied
Each 1 mg/dL increase in serum phosphorus was associated with an 18% higher risk of death in people with chronic kidney disease
Each 1 mg/dL increase in serum phosphorus was associated with an 18% higher risk of death in people with chronic kidney disease
Related Health Concerns
Study Details
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