systematic_review
    2016
    High Quality

    Coenzyme Q10 for heart failure (Cochrane) — Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension

    Ho MJ, Li ECK, Wright JM

    Published in Cochrane Database of Systematic Reviews

    Methodology

    Cochrane systematic review and meta-analysis of randomized, placebo-controlled trials of coenzyme Q10 for primary hypertension.

    Key Findings

    Pooled analysis of the higher-quality trials found no statistically significant effect of CoQ10 on systolic or diastolic blood pressure.

    Conclusions

    There is currently no reliable evidence that coenzyme Q10 lowers blood pressure in primary hypertension.

    Limitations

    Few eligible trials and small total sample; earlier positive findings were driven by lower-quality studies.

    Supplements Studied

    CoQ10
    Compound

    Pooled analysis found no statistically significant effect of CoQ10 on systolic or diastolic blood pressure.

    Outcomes Measured

    Pooled analysis found no statistically significant effect of CoQ10 on blood pressure.

    Pooled analysis of the higher-quality trials found no statistically significant effect of CoQ10 on systolic or diastolic blood pressure.

    Related Health Concerns

    Study Details

    Year:2016
    Sample Size:120
    Quality Score:10/10

    Disclosures

    Funding

    Cochrane (no commercial funding)

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.