The effects of betaine supplementation on fluid balance and heat tolerance during passive heat stress in men
Willingham BD, Renteria LI, Ragland TJ, Ormsbee MJ
Published in Physiological Reports
Key Findings
Seven days of betaine loading produced no significant condition-by-time interactions for plasma volume, osmolality or other fluid-balance and heat-tolerance markers during passive heat exposure.
Conclusions
Betaine did not improve fluid balance or heat tolerance despite its osmolyte properties.
Limitations
Only 11 recreationally active men, passive heat stress rather than exercise heat stress.
Supplements Studied
Consuming intracellular osmolytes, like betaine (BET), may attenuate symptoms of heat stress.
Outcomes Measured
During heat exposure, significant time effects but no condition x time interactions, were found for plasma characteristics
Study Details
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This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.