rct
    2023
    High Quality

    The efficacy and safety of β-nicotinamide mononucleotide supplementation in healthy middle-aged adults: a randomized, multicentre, double-blind, placebo-controlled, dose-dependent clinical trial

    Yi L, Maier AB, Tao R

    Published in GeroScience

    Key Findings

    NMN raised blood NAD+ dose-dependently and improved walking distance and a subjective wellbeing score, but not most other endpoints.

    Conclusions

    Biomarker change with limited functional translation.

    Limitations

    Industry funded, self-reported outcomes.

    Supplements Studied

    NMN
    Compound

    NMN raised blood NAD+ dose-dependently and improved walking distance, but most endpoints were unchanged.

    Vitamin B3
    Vitamin

    NMN raised blood NAD+ dose-dependently and improved walking distance and a subjective wellbeing score, but not most other endpoints.

    Outcomes Measured

    Anti-Aging Effects

    NMN raised NAD+ dose-dependently but improved few functional ageing endpoints.

    Study Details

    Year:2023
    Sample Size:80
    Duration:8 weeks
    Quality Score:7/10

    Access Study

    View on DOIView on PubMedOriginal Source

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.