rct
    2018
    High Quality

    Effect of nicotinamide riboside on skeletal muscle and metabolic health: a randomized, placebo-controlled trial

    Dollerup OL, Christensen B, Svart M

    Published in American Journal of Clinical Nutrition

    Key Findings

    Twelve weeks of an NAD+ precursor did not improve insulin sensitivity, mitochondrial function or body composition in obese men.

    Conclusions

    Well-designed null result for NAD+ boosting.

    Limitations

    Male-only, obese cohort.

    Supplements Studied

    NADH
    Compound

    An NAD+ precursor did not improve insulin sensitivity, mitochondrial function or body composition over 12 weeks.

    Vitamin B3
    Vitamin

    Twelve weeks of an NAD+ precursor did not improve insulin sensitivity, mitochondrial function or body composition in obese men.

    Outcomes Measured

    Increased Energy Production

    Mitochondrial function and metabolic health were unchanged after 12 weeks of NAD+ precursor supplementation.

    Electron Transport Chain Support

    Twelve weeks of an NAD+ precursor did not improve insulin sensitivity, mitochondrial function or body composition in obese men.

    Insulin Sensitivity

    Twelve weeks of an NAD+ precursor did not improve insulin sensitivity, mitochondrial function or body composition in obese men.

    Study Details

    Year:2018
    Sample Size:40
    Duration:12 weeks
    Quality Score:7/10

    Access Study

    View on DOIView on PubMedOriginal Source

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.