Hesperidin in orange juice improves human endothelial function in subjects with elevated blood pressure and stage 1 hypertension: a randomized, controlled trial (Citrus study)
Valls RM, Pedret A, Calderon-Perez L, Llaurado E, Pla-Paga L, Companys J
Published in Journal of Functional Foods
Methodology
Randomised, parallel, double-blind, controlled trial of hesperidin-enriched orange juice versus control juice over 12 weeks in adults with elevated blood pressure
Key Findings
Hesperidin-enriched juice improved endothelial function and reduced systolic blood pressure and inflammatory biomarkers relative to control.
Conclusions
Hesperidin from orange juice modestly improves vascular function in pre-hypertensive adults.
Limitations
Food-matrix intervention; effects not attributable to hesperidin alone.
Supplements Studied
Hesperidin-enriched juice improved endothelial function and reduced systolic blood pressure.
Outcomes Measured
Hesperidin-enriched juice improved endothelial function in adults with elevated blood pressure.
Related Health Concerns
Study Details
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