systematic_review
    2021
    High Quality

    A systematic review of the effect of L-tryptophan supplementation on mood and emotional functioning

    Kikuchi AM, Tanabe A, Iwahori Y

    Published in Journal of Dietary Supplements

    Key Findings

    Most trials in healthy adults reported reduced depressive and anxious mood with tryptophan intake, though effects were small and inconsistent.

    Conclusions

    Modest mood effects in non-clinical populations.

    Limitations

    Heterogeneous designs, small samples.

    Supplements Studied

    L-Tryptophan
    Amino Acid

    Most trials in healthy adults reported reduced depressive and anxious mood with tryptophan, though effects were small.

    Outcomes Measured

    L-tryptophan supplementation was associated with improvements in mood and emotional functioning in several controlled studies.

    Tryptophan supplementation improved mood and sleep measures consistent with increased central serotonin synthesis

    Related Health Concerns

    Study Details

    Year:2021
    Quality Score:7/10

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.