Schisandra chinensis fruit modulates the gut microbiota composition in association with metabolic markers in obese women: a randomized, double-blind placebo-controlled study
Song MY, Wang JH, Eom T, Kim H
Published in Nutrition Research
Methodology
Double-blind placebo-controlled trial in 28 obese women receiving Schisandra chinensis fruit or placebo for 12 weeks, with anthropometry, blood markers and faecal microbiota analysis by DGGE and qPCR
Key Findings
Anthropometric and metabolic differences between groups were not statistically significant, though the Schisandra group trended toward lower waist circumference, fat mass, glucose, triglycerides and liver enzymes.
Conclusions
A null primary result with hypothesis-generating microbiota and metabolic trends.
Limitations
Only 28 participants; underpowered; single centre; exploratory microbiota methods.
Supplements Studied
Although the values did not differ significantly between the 2 groups, the SCF group tended to show a greater decrease in waist circumference, fat mass, fasting blood glucose, triglycerides, aspartate aminotransferase, and alanine aminotransferase than the placebo group.
Outcomes Measured
the SCF group tended to show a greater decrease in waist circumference, fat mass, fasting blood glucose, triglycerides, aspartate aminotransferase, and alanine aminotransferase than the placebo group
Study Details
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Disclosures
Funding
Not reported
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