meta_analysis
    2022
    High Quality

    Effect of Casein Hydrolysate on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

    Zhou S, Xu T, Zhang X, Luo J, An P

    Published in Nutrients

    Methodology

    Systematic review and meta-analysis of randomized controlled trials of casein hydrolysate supplementation on blood pressure, lipids and glucose

    Key Findings

    Casein hydrolysate reduced systolic blood pressure by 3.20 mmHg and diastolic blood pressure by 1.50 mmHg, with no effect on total cholesterol, LDL, HDL, triglycerides or glucose.

    Conclusions

    Benefit of casein hydrolysate appears limited to modest blood pressure lowering; lipid and glycaemic risk factors are unchanged.

    Limitations

    Heterogeneous hydrolysate preparations and doses; mostly short-duration trials with surrogate endpoints.

    Supplements Studied

    Casein hydrolysate significantly reduced systolic blood pressure by 3.20 mmHg (-4.53 to -1.87 mmHg) and diastolic blood pressure by 1.50 mmHg (-2.31 to -0.69 mmHg).

    Related Health Concerns

    Study Details

    Year:2022
    Quality Score:9/10

    Disclosures

    Funding

    Not specified

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.