Association of prebiotic/probiotic intake with MASLD: evidence from NHANES and randomized controlled trials
Wang S, Zhang R, Guo P, Yang H
Published in The EPMA Journal
Methodology
NHANES 2001-2018 cross-sectional analysis of 5014 adults combined with a meta-analysis of randomized controlled trials of probiotics, prebiotics or yogurt lasting at least 6 months in MASLD or NASH.
Key Findings
Probiotic/prebiotic intake was associated with MASLD status in NHANES, and pooled trials reported liver-function improvements over at least 6 months.
Conclusions
Prebiotics and probiotics may modestly benefit liver function in MASLD, though observational and trial evidence differ in strength.
Limitations
Cross-sectional component cannot establish causality; trials small with surrogate endpoints.
Supplements Studied
The analysis included randomized controlled trials of liver function in patients with MASLD or nonalcoholic steatohepatitis treated with probiotics, prebiotics, or yogurt for a minimum of 6 months.
Related Health Concerns
Study Details
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Disclosures
Funding
Not reported
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.