meta_analysis
    2022
    High Quality

    Therapeutic Potential of Artichoke in the Treatment of Fatty Liver: A Systematic Review and Meta-Analysis

    Kamel AM, Farag MA

    Published in Journal of Medicinal Food

    Methodology

    Random-effects meta-analysis of 5 RCTs of artichoke leaf extract in NAFLD patients (PROSPERO CRD42020182502)

    Key Findings

    ALT (SMD 1.1), AST (SMD 1.01), total cholesterol (SMD 0.98), LDL (SMD 0.96) and triglycerides (SMD 0.95) all significantly reduced versus control.

    Conclusions

    Evidence from RCTs supports artichoke leaf extract as a hepatoprotective agent in NAFLD patients.

    Limitations

    Only five small RCTs from a limited number of research groups; no histological or hard clinical outcomes.

    Supplements Studied

    The current review provides evidence from RCTs to support the use of ALE as a hepatoprotective agent in NAFLD patients

    Outcomes Measured

    The current review provides evidence from RCTs to support the use of ALE as a hepatoprotective agent in NAFLD patients

    Related Health Concerns

    Study Details

    Year:2022
    Sample Size:333
    Quality Score:7/10

    Disclosures

    Funding

    Not reported

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.