Potent antihypertensive action of dietary flaxseed in hypertensive patients (FlaxPAD)
Rodriguez-Leyva D, Weighell W, Edel AL, LaVallee R, Dibrov E, Pinneker R, Maddaford TG, Ramjiawan B, Aliani M, Guzman R, Pierce GN
Published in Hypertension
Methodology
Double-blind randomized placebo-controlled trial of 30 g/day milled flaxseed for 6 months in patients with peripheral artery disease.
Key Findings
Flaxseed lowered systolic blood pressure by about 10 mmHg and diastolic by about 7 mmHg versus placebo, with largest effects in those hypertensive at baseline.
Conclusions
Milled flaxseed produced a clinically meaningful antihypertensive effect over 6 months.
Limitations
Single-centre, specific PAD population, whole milled seed rather than oil, self-reported adherence.
Supplements Studied
Systolic and diastolic blood pressure were roughly 10 and 7 mmHg lower in the flaxseed group than in the placebo group.
Outcomes Measured
Systolic and diastolic blood pressure were roughly 10 and 7 mmHg lower in the flaxseed group than in the placebo group.
Related Health Concerns
Study Details
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