Probiotics for the management of irritable bowel syndrome: a systematic review and three-level meta-analysis
Xie P, Luo M, Deng X, Fan J, Xiong L
Published in International Journal of Surgery
Methodology
Systematic review and three-level meta-analysis of randomised controlled trials of probiotics for IBS symptom severity, abdominal pain and quality of life
Key Findings
Probiotics produced small significant reductions in global IBS symptom severity and abdominal pain, with effects varying widely by strain.
Conclusions
Probiotic benefit in IBS is real but small and highly strain-dependent.
Limitations
High heterogeneity; many small trials at risk of bias.
Supplements Studied
Probiotics produced small significant reductions in global IBS symptom severity and abdominal pain, with effects varying widely by strain.
Probiotics produced small significant reductions in global IBS symptom severity and abdominal pain, with effects varying widely by strain.
Probiotics produced small significant reductions in global IBS symptom severity and abdominal pain, with effects varying widely by strain.
Outcomes Measured
Probiotics produced small significant reductions in global IBS symptom severity and abdominal pain, with effects varying widely by strain.
Related Health Concerns
Study Details
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