Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans
Timmers S, Konings E, Bilet L, Houtkooper RH, van de Weijer T, Goossens GH, Hoeks J, van der Krieken S, Ryu D, Kersten S, Moonen-Kornips E, Hesselink MKC, Kunz I, Schrauwen-Hendriks VB, Blaak EE, Auwerx J, Schrauwen P
Published in Cell Metabolism
Key Findings
Resveratrol 150 mg/day for 30 days lowered systolic blood pressure, liver fat and inflammatory markers and improved muscle mitochondrial function in obese men.
Conclusions
Short-term resveratrol produced calorie restriction-like metabolic changes in obese men.
Limitations
Eleven participants; 30 days; surrogate endpoints only.
Supplements Studied
Resveratrol 150 mg/day for 30 days lowered systolic blood pressure, liver fat and inflammatory markers in obese men.
Outcomes Measured
Resveratrol 150 mg/day lowered systolic blood pressure and liver fat in obese men.
Resveratrol 150 mg/day for 30 days lowered systolic blood pressure, liver fat and inflammatory markers and improved muscle mitochondrial function in obese men.
Study Details
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