Effects of Quercetin on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Serban MC, Sahebkar A, Zanchetti A, Mikhailidis DP, Banach M
Published in Journal of the American Heart Association
Methodology
Random/fixed-effects meta-analysis of 7 placebo-controlled RCTs (9 treatment arms) searched to January 2015
Key Findings
Quercetin reduced systolic BP by 3.04 mm Hg (95% CI -5.75 to -0.33) and diastolic BP by 2.63 mm Hg (95% CI -3.26 to -2.01). Doses >=500 mg/day drove the effect; doses <500 mg/day were not significant.
Conclusions
Quercetin supplementation produces small but statistically significant reductions in both systolic and diastolic blood pressure.
Limitations
Small pooled sample, few trials, heterogeneous populations and formulations; indirect dose comparisons were not statistically significant.
Supplements Studied
significant reductions both in systolic BP (WMD: -3.04 mm Hg) and diastolic BP (WMD: -2.63 mm Hg) following supplementation with quercetin
Outcomes Measured
there was a significant systolic BP and diastolic BP-reducing effect in randomized controlled trials with doses >=500 mg/day
significant reductions both in systolic BP and diastolic BP following supplementation with quercetin
Related Health Concerns
Study Details
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This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.