meta_analysis
    2025
    High Quality

    Impacts of supplementation with milk proteins on inflammation: a systematic review and meta-analysis

    Mohammadi S, Ashtary-Larky D, Mehrbod M, Kouhi Sough N, Salehi Omran H

    Published in Inflammopharmacology

    Methodology

    Systematic review and dose-response meta-analysis of 53 randomized controlled trials of whey, casein or milk protein on cytokines and adipokines in adults

    Key Findings

    No substantial effects on CRP, TNF-alpha, adiponectin or leptin; a small significant reduction in IL-6 (-0.25 pg/mL).

    Conclusions

    Milk protein supplementation, including casein, does not meaningfully alter systemic inflammatory markers.

    Limitations

    Mixed protein types pooled; heterogeneous populations and assay methods; single significant marker may reflect chance.

    Supplements Studied

    This study revealed that MP supplementation may not have any considerable impacts on the levels of cytokines and adipokines.

    Related Health Concerns

    Study Details

    Year:2025
    Quality Score:9/10

    Disclosures

    Funding

    Not specified

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.