rct
    2024
    High Quality

    Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial

    Unknown authors

    Published in Nature Aging

    Key Findings

    Nicotinamide riboside showed indications of upregulated gene pathways related to genomic integrity in the airways and reduced epigenetic aging, possibly via reduced cellular senescence.

    Conclusions

    NAD+ precursor supplementation may support genome maintenance pathways, though findings are exploratory.

    Supplements Studied

    NMN
    Compound

    Treatment with NR showed indications of upregulated gene pathways related to genomic integrity in the airways and reduced epigenetic aging.

    Vitamin B3
    Vitamin

    Nicotinamide riboside showed indications of upregulated gene pathways related to genomic integrity in the airways and reduced epigenetic aging, possibly via reduced cellular senescence.

    Outcomes Measured

    Treatment with NR showed indications of upregulated gene pathways related to genomic integrity in the airways and reduced epigenetic aging, possibly through a reduction in cellular senescence.

    Study Details

    Year:2024
    Quality Score:8/10

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