A placebo controlled randomized clinical trial of Crocus sativus L. (saffron) on depression and food craving among overweight women with mild to moderate depression
Akhondzadeh S, Mostafavi SA, Keshavarz SA, Mohammadi MR, Hosseini S
Published in Journal of Clinical Pharmacy and Therapeutics
Methodology
12-week double-blind placebo-controlled randomized trial of 30 mg/day saffron capsules in overweight women with mild-to-moderate depression
Key Findings
Saffron improved depression scores compared with placebo, with associated changes in food craving measures in overweight depressed women
Conclusions
Saffron may help craving in the context of improved mood, not as a standalone appetite agent
Limitations
High dropout (52 completers), depression-specific population, short follow-up
Supplements Studied
Participants were randomly assigned into one of the two groups receiving daily either 30 mg of Crocus sativus capsules (15 mg twice/day) or placebo capsules (twice/day).
Related Health Concerns
Study Details
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