Benefits, side effects, and uses of Hericium erinaceus as a supplement: a systematic review
Menon A, et al.
Published in Frontiers in Nutrition
Methodology
Systematic review of human interventional and observational studies of Hericium erinaceus (lion's mane) supplementation, summarising cognitive, mood, metabolic and safety outcomes.
Key Findings
Across a small number of mostly short human trials, Hericium erinaceus produced modest improvement in cognitive scores (small mean MMSE gain) and some mood measures, with generally mild gastrointestinal or dermatological side effects.
Conclusions
Hericium erinaceus shows preliminary benefit for cognitive function, with a modest mean MMSE increase.
Limitations
Few small trials with heterogeneous preparations and doses, short follow-up, risk of bias, and reliance on screening instruments like MMSE that are insensitive to small changes.
Supplements Studied
HE is effective in neuroprotection, enhancing cognitive function, preventing and alleviating cancer, promoting gut health, and improving symptoms of anxiety and depression.
Related Health Concerns
Study Details
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This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.