Efficacy and safety of white willow bark (Salix alba) extracts
Shara M, Stohs SJ
Published in Phytotherapy Research
Methodology
Narrative systematic review of pharmacology, clinical efficacy and safety data for standardised Salix alba bark extracts.
Key Findings
Salicin is metabolised to salicylic acid with weak COX inhibition; anti-inflammatory polyphenols may contribute, and adverse events are generally mild although salicylate cautions apply.
Conclusions
Willow bark extracts have an acceptable safety profile at usual doses but efficacy data remain limited to musculoskeletal pain.
Limitations
Narrative review without quantitative pooling; limited long-term safety data.
Supplements Studied
Salicin is metabolised to salicylic acid with weak COX inhibition, and adverse events are generally mild although salicylate cautions apply.
Related Health Concerns
Study Details
Access Study
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.