Saffron for major depressive disorder and anhedonia: a systematic review and meta-analysis
Hausenblas HA, Saha D, Dubyak PJ, Anton SD
Published in Journal of Integrative Medicine
Methodology
Meta-analysis of randomized controlled trials of saffron versus placebo or antidepressants for depressive symptoms including loss of interest and pleasure.
Key Findings
Saffron significantly outperformed placebo and matched standard antidepressants on depression severity including anhedonia items.
Conclusions
Saffron improves depressive symptoms that include blunted pleasure response.
Limitations
Nearly all trials conducted in Iran; small samples.
Supplements Studied
Saffron significantly outperformed placebo and matched standard antidepressants on depression severity
Outcomes Measured
Saffron significantly outperformed placebo and matched standard antidepressants on depression severity including anhedonia items
Saffron significantly outperformed placebo and matched standard antidepressants on depression severity
Saffron significantly outperformed placebo on depression severity including anhedonia items
Saffron significantly outperformed placebo and matched standard antidepressants on depression severity
Related Health Concerns
Study Details
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