Effect of L-Citrulline Supplementation on Blood Pressure: a Systematic Review and Meta-Analysis of Clinical Trials
Barkhidarian B, Khorshidi M, Shab-Bidar S, Hashemi B
Published in Current Hypertension Reports
Methodology
Systematic review and meta-analysis of clinical trials assessing oral L-citrulline supplementation on systolic and diastolic blood pressure.
Key Findings
L-citrulline supplementation significantly reduced systolic blood pressure, with a smaller and less consistent effect on diastolic blood pressure.
Conclusions
L-citrulline modestly lowers systolic blood pressure in short-term trials.
Limitations
Short trial durations, small samples, heterogeneous doses and populations, surrogate endpoint only.
Supplements Studied
L-citrulline supplementation significantly reduced systolic blood pressure.
Outcomes Measured
L-citrulline supplementation significantly reduced systolic blood pressure.
Related Health Concerns
Study Details
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This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.