Effects of creatine supplementation on muscle cell volumisation and intracellular water: a randomized controlled trial
Powers ME, Arnold BL, Weltman AL, Perrin DH, Mistry D, Kahler DM
Published in Journal of Athletic Training
Methodology
Randomized placebo-controlled trial measuring body water compartments and body mass during creatine loading and maintenance.
Key Findings
Creatine increased total and intracellular body water alongside body mass, consistent with muscle cell volumisation.
Conclusions
Creatine drives cell swelling that contributes to muscle fullness.
Limitations
Short duration; indirect measures of cell volume.
Supplements Studied
Creatine increased total and intracellular body water alongside body mass, consistent with muscle cell volumisation
Outcomes Measured
Creatine increased total and intracellular body water alongside body mass, consistent with muscle cell volumisation
Study Details
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This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.