meta_analysis
    2025
    High Quality

    The Effect of Aged Garlic Supplementation on Blood Pressure and Lipid Profile: A Dose-Response GRADE-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials

    Ghaedi E, Hadi A, Askarpour M

    Published in Phytotherapy Research

    Methodology

    GRADE-assessed dose-response systematic review and meta-analysis of randomized trials of aged garlic extract on blood pressure and lipids.

    Key Findings

    Aged garlic significantly reduced systolic and diastolic blood pressure and total cholesterol, with low-to-moderate certainty evidence and dose-dependent blood pressure effects.

    Conclusions

    Aged garlic extract lowers blood pressure modestly; lipid effects are smaller and less certain.

    Limitations

    Low-to-moderate GRADE certainty; heterogeneity in extract standardisation.

    Supplements Studied

    Aged garlic supplementation significantly reduced systolic and diastolic blood pressure and total cholesterol with low-to-moderate certainty evidence.

    Outcomes Measured

    Aged garlic supplementation significantly reduced systolic and diastolic blood pressure with dose-dependent effects.

    Related Health Concerns

    Study Details

    Year:2025
    Sample Size:1,500
    Duration:12 weeks
    Quality Score:8/10

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.