Effect of Carnosine or beta-Alanine Supplementation on Markers of Glycemic Control and Insulin Resistance in Humans and Animals: A Systematic Review and Meta-analysis
Matthews JJ, Dolan E, Swinton PA, Santos L, Artioli GG, Turner MD, Elliott-Sale KJ, Sale C
Published in Advances in Nutrition
Abstract
Systematic review and meta-analysis of carnosine and beta-alanine on glycemic control and insulin resistance.
Key Findings
Pooled human trials showed carnosine or beta-alanine supplementation reduced HbA1c and fasting glucose in participants with impaired glucose metabolism, with little effect in metabolically healthy individuals.
Conclusions
Carnosine may improve glycemic control where metabolism is already impaired.
Limitations
Few human trials, animal data pooled separately, heterogeneous dosing.
Supplements Studied
Pooled human trials showed carnosine or beta-alanine supplementation reduced HbA1c and fasting glucose in participants with impaired glucose metabolism, with little effect in metabolically healthy individuals.
Pooled human trials showed carnosine or beta-alanine supplementation reduced HbA1c and fasting glucose in participants with impaired glucose metabolism, with little effect in metabolically healthy individuals.
Outcomes Measured
Pooled human trials showed carnosine or beta-alanine supplementation reduced HbA1c and fasting glucose in participants with impaired glucose metabolism, with little effect in metabolically healthy individuals.
Pooled human trials showed carnosine or beta-alanine supplementation reduced HbA1c and fasting glucose in participants with impaired glucose metabolism, with little effect in metabolically healthy individuals.
Related Health Concerns
Study Details
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