Immune

    Allergy Relief

    Relief from seasonal and environmental allergy symptoms.

    TL;DR

    Seasonal allergy symptoms respond best to nasal saline, allergen avoidance, and antihistamines; among supplements, quercetin, spirulina, and vitamin C have modest human evidence as adjuncts. Start before pollen season.

    Why It Matters

    Allergic rhinitis is IgE-mediated mast cell activation with histamine, leukotriene, and cytokine release. Supplements with mast-cell-stabilizing or anti-inflammatory properties (quercetin, vitamin C, spirulina) show small-to-moderate effect sizes in RCTs, inferior to intranasal steroids but useful for mild symptoms or as add-ons.

    How to Measure

    Track Total Nasal Symptom Score (congestion, rhinorrhea, sneezing, itching) daily during season; note rescue antihistamine use.

    Biomarkers

    Total IgE (context only)
    Blood eosinophils
    Symptom scores (TNSS)

    Optimization Protocol

    Begin 4–6 weeks before season: Quercetin 500 mg twice daily; Vitamin C 1–2 g/day; Spirulina 2 g/day has positive RCT data. Continue standard care (intranasal steroid/antihistamine) as prescribed.

    Lifestyle Levers

    • HEPA filtration
    • Shower after outdoor exposure
    • Keep windows closed on high-pollen days
    • Nasal saline rinses

    Supporting Supplements

    Supporting Research

    Frequently Asked Questions

    Typical Timeframe

    2–4 weeks of loading before season; effects assessed across a season.

    Research Summary

    Studies5
    Supplements3

    My Notes

    Sign in to add personal notes

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.