rct
2018
High Quality
AR101 oral immunotherapy for peanut allergy
PALISADE Group of Clinical Investigators, Vickery BP, Vereda A, Casale TB, Beyer K, du Toit G, Burks AW
Published in New England Journal of Medicine
Key Findings
67.2% of AR101-treated participants tolerated 600 mg peanut protein versus 4.0% on placebo, with more adverse events and epinephrine use in the treated group.
Conclusions
Oral immunotherapy raises reaction thresholds but does not cure allergy.
Limitations
High dropout; efficacy not shown in adults.
Outcomes Measured
AR101 immunotherapy raised the tolerated dose of peanut protein compared with placebo.
Related Health Concerns
Study Details
Year:2018
Sample Size:551
Duration:52 weeks
Quality Score:9/10
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