Vitamin D for Bone Mineral Density
Vitamin D with adequate calcium reduces fracture risk in deficient and institutionalized older adults. In already-replete community-dwelling adults, large trials (VITAL) showed no BMD benefit — test and correct, do not megadose.
Overview
How It Works
Dosing & Protocol
Dosing aimed at bone mineral density
| Situation | Vitamin D | Target | Notes |
|---|---|---|---|
| Maintenance in sufficient adults | 800-1,000 IU D3 daily | 20-30 ng/mL | Food-based calcium alongside |
| Confirmed deficiency | 1,000-4,000 IU D3 daily (clinician-guided) | 30-50 ng/mL | Re-test after 3-4 months |
| Malabsorption conditions | Often higher; supervised | 30-50 ng/mL | Treat the underlying cause; levels monitored |
Evidence
Effects of vitamin D supplements on bone mineral density: a systematic review and meta-analysis
Vitamin D supplementation had no clinically meaningful effect on bone mineral density at most sites.
Bones of contention: bone mineral density recovery in celiac disease - a systematic review
Grace-Farfaglia P
Calcium and vitamin D repletion supports but does not replace gluten-free adherence for bone recovery.
Safety
Interactions & Conflicts
Interactions to know
| Interacts with | Severity | Mechanism | Action |
|---|---|---|---|
| — | — | ||
| — | — | ||
| — | — | ||
| — | — |
References
Frequently Asked Questions
Medical Disclaimer
The information provided on this website is for educational and informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any supplement regimen.
Individual results may vary. The statements on this website have not been evaluated by the Food and Drug Administration. Products and information are not intended to diagnose, treat, cure, or prevent any disease.