Vitamin D for Autoimmune Modulation
Vitamin D 2000 IU/day reduced confirmed autoimmune disease over five years in the largest randomised trial to address the question.
Overview
How It Works
Dosing & Protocol
Dosing for immune modulation
| Goal | Vitamin D | Target | Notes |
|---|---|---|---|
| Autoimmune risk reduction (VITAL dose) | 2,000 IU D3 daily | Sufficiency maintained | Effect emerged over years of consistent use |
| Correcting deficiency first | Clinician-guided replacement | 30-50 ng/mL | Re-test after 3-4 months |
| Existing autoimmune disease | Maintain sufficiency; adjunct only | 30-50 ng/mL | Coordinate with your specialist |
Evidence
Vitamin D and marine omega 3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial
Hahn J, Cook NR, Alexander EK
Vitamin D reduced confirmed incident autoimmune disease by 22% (HR 0.78).
Safety
Interactions & Conflicts
Interactions to know
| Interacts with | Severity | Mechanism | Action |
|---|---|---|---|
| — | — | ||
| — | — | ||
| — | — | ||
| — | — |
References
Frequently Asked Questions
Medical Disclaimer
The information provided on this website is for educational and informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any supplement regimen.
Individual results may vary. The statements on this website have not been evaluated by the Food and Drug Administration. Products and information are not intended to diagnose, treat, cure, or prevent any disease.