Outcome
    Limited

    Quercetin for Respiratory Health

    Quercetin has plausible antiviral and mast-cell stabilising activity with weak human evidence.

    Overview

    Quercetin has plausible antiviral and mast-cell stabilising activity with weak human evidence.

    Verdict

    Insufficient evidence

    How It Works

    Inhibits mast cell degranulation and shows in vitro antiviral and zinc ionophore activity.

    Dosing & Protocol

    Typical dose

    Recommended dose
    500-1000mg/day, ideally with bromelain or in a phytosome form
    Expected timeframe
    4-12 weeks

    Protocol

    form
    Bioavailability-enhanced quercetin
    duration
    Trials ran 2-12 weeks
    co factor
    Evidence is insufficient. The rationale is reasonable - quercetin stabilises mast cells, reduces airway inflammatory mediators in vitro and improved outcomes in animal models of asthma and lung injury - and a widely cited trial in ultramarathon runners found reduced upper respiratory infection incidence after extreme exertion. That finding has not translated: subsequent trials in general and community populations have shown inconsistent or absent effects, trials in asthma are small and inconclusive, and the COVID-19 trials that generated considerable attention were small, poorly controlled and do not support the conclusions drawn from them. No adequately powered trial has shown improvement in lung function, asthma control or respiratory infection outcomes in a general population.
    titration
    Not applicable - no dose has reliably improved respiratory outcomes
    starting dose
    Not established. Trials used 500-1,000 mg/day in divided doses with food

    Evidence

    What the studies say

    Small trials suggest reduced upper respiratory illness in stressed athletes at high doses. Bioavailability is poor without co-formulation and outcome data is thin.

    No studies are yet linked to both Quercetin and Respiratory Health.

    Safety

    Caveats

    Poor absorption in standard forms. Interacts with some antibiotics and ciclosporin.

    Less likely to help if

    Everyone - no respiratory outcome has been reliably demonstrated, and asthma needs proper treatment.

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    Individual results may vary. The statements on this website have not been evaluated by the Food and Drug Administration. Products and information are not intended to diagnose, treat, cure, or prevent any disease.