Oil
    Moderate Evidence

    Ahiflower Oil

    Buglossoides arvensis

    TL;DR

    A plant-based omega-3 oil from Buglossoides arvensis whose SDA content converts to EPA in the body several times more efficiently than the ALA in flax or chia.

    Ideal For

    • Vegans and vegetarians who want real EPA conversion
    • People who dislike fish oil aftertaste or reflux
    • Those seeking combined ALA/SDA/GLA coverage in one oil

    Avoid If

    • You need DHA specifically (pair with algae oil)
    • You are on high-dose anticoagulants without medical guidance

    Frequently Asked Questions

    Overview

    Ahiflower oil is pressed from the seeds of Buglossoides arvensis, a UK-bred crop, and is notable for containing stearidonic acid (SDA, roughly 18-20%) alongside a high alpha-linolenic acid (ALA) fraction and a meaningful dose of GLA. SDA bypasses the rate-limiting delta-6-desaturase step, so human trials show ahiflower raises circulating EPA 3-4x more effectively than an equivalent ALA dose from flaxseed oil. That makes it one of the few genuinely compelling vegan EPA sources, though it does not raise DHA. Positioning: a fish-oil alternative for plant-based eaters who want real EPA status rather than theoretical conversion.

    How It Works

    • SDA converts to EPA without the delta-6-desaturase bottleneck that limits flax and chia
    • Raises plasma and cell-membrane EPA, substrate for anti-inflammatory eicosanoids and resolvins
    • GLA fraction converts to DGLA, precursor of the anti-inflammatory series-1 prostaglandin PGE1
    • Does not meaningfully raise DHA, which requires separate algae-oil supplementation

    Benefits & Outcomes

    No linked outcomes yet. Research is ongoing.

    Supporting Research
    9 studies

    Consumption of Buglossoides arvensis seed oil is safe and increases tissue long-chain n-3 fatty acid content more than flax seed oil: results of a phase I randomised clinical trial

    Score: 5/10
    2016
    rct
    n=40

    Lefort N, LeBlanc R, Giroux MA +1 more

    Ahiflower oil raised EPA and total long-chain n-3 content more than flaxseed oil over 28 days, with no adverse safety signals, but did not raise DHA.

    View source

    Dietary Buglossoides arvensis oil increases circulating n-3 polyunsaturated fatty acids in a dose-dependent manner and enhances lipopolysaccharide-stimulated whole blood interleukin-10: a randomized placebo-controlled trial

    Score: 6/10
    2017
    rct
    n=88

    Lefort N, LeBlanc R, Surette ME

    Circulating n-3 fatty acids rose dose-dependently and LPS-stimulated whole blood interleukin-10 production increased in healthy adults.

    View source

    Stearidonic acid improves eicosapentaenoic acid status: studies in humans and cultured hepatocytes

    Score: 8/10
    2024
    rct
    n=29

    Seidel U, Eberhardt K, Wiebel M +7 more

    The consumption of ahiflower oil improves the circulating levels of EPA and EPA-derived oxylipins in humans.

    View source

    Dietary intake of stearidonic acid-enriched soybean oil increases the omega-3 index: randomized, double-blind clinical study of efficacy and safety

    Score: 9/10
    2010
    rct
    n=252

    Lemke SL, Vicini JL, Su H +4 more

    SDA-enriched soybean oil increased the omega-3 index by raising erythrocyte EPA concentrations.

    View source

    Consumption of echium oil increases EPA and DPA in blood fractions more efficiently compared to linseed oil in humans

    Score: 8/10
    2016
    rct
    n=105

    Kuhnt K, Weiss S, Kiehntopf M +1 more

    Daily intake of SDA-containing EO is a better supplement than LO for increasing EPA and DPA in blood. However, neither EO nor LO maintained blood DHA status in the absence of fish/seafood consumption.

    View source

    Consumption of stearidonic acid-rich oil in foods increases red blood cell eicosapentaenoic acid

    Score: 8/10
    2013
    rct

    Lemke SL, Maki KC, Hughes G +6 more

    Consumption of stearidonic acid-enriched soybean oil incorporated into common foods increased RBC %EPA in healthy men and women.

    View source

    Stearidonic acid-enriched soybean oil increased the omega-3 index, an emerging cardiovascular risk marker

    Score: 7/10
    2008
    rct
    n=45

    Harris WS, Lemke SL, Hansen SN +7 more

    Compared to baseline, average omega-3 index levels increased 19.5% in the SDA group and 25.4% in the EPA group (p<0.05 for both, vs. control). DHA did not change in any group.

    View source

    Stearidonic acid as a supplemental source of omega-3 polyunsaturated fatty acids to enhance status for improved human health

    Score: 7/10
    2013
    systematic_review

    Walker CG, Jebb SA, Calder PC

    This review discusses the currently available evidence that increased SDA consumption can increase red blood cell EPA content, although this is less than the effect of supplementation directly with EPA.

    View source

    Effects of dietary stearidonic acid on biomarkers of lipid metabolism

    Score: 7/10
    2012
    systematic_review

    Whelan J, Gouffon J, Zhao Y

    Supplementing SDA at doses of 3.7-4.2 g/d, of which the bioequivalence to EPA is <=1 g/d, had little impact on modifying circulating TG and total, LDL, and HDL cholesterol.

    View source

    Safety Information

    Potential Side Effects

    Generally well tolerated; occasional mild GI upset or loose stools at higher doses.

    Drug Interactions

    • anticoagulants
    • antiplatelet drugs

    Pregnancy & Breastfeeding

    Pregnancy: insufficient_data

    Breastfeeding: insufficient_data

    Dosage Guidelines

    Dosage Used in Studies

    Consult healthcare provider

    Forms Compared

    Food & Timing

    With meals containing fat

    Medical Disclaimer

    The information provided on this website is for educational and informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any supplement regimen.

    Individual results may vary. The statements on this website have not been evaluated by the Food and Drug Administration. Products and information are not intended to diagnose, treat, cure, or prevent any disease.