crossover
    2019

    A randomized trial to assess beverage hydration index in healthy older adults

    Clarke MM, Stanhewicz AE, Wolf ST, Cheuvront SN, Kenefick RW, Kenney WL

    Published in Am J Clin Nutr, Vol. 109 (6), pp. 1640-1647

    Methodology

    Randomised crossover in 12 young (mean 23 years) and 12 older (mean 67 years) adults. On five visits each drank 1 L of water or one of four commercial drinks with 20, 30, 45 or 60 mmol/L sodium (glucose- or amino-acid-based); blood and urine were sampled over 4 hours.

    Key Findings

    In young adults BHI rose with sodium content; the 60 mmol/L drink had the highest BHI (1.24 vs 1.00 for water, P = 0.01). In older adults the 30 mmol/L amino-acid drink had the highest BHI (1.20, P < 0.01), and the 60 mmol/L drink was still changing beyond 2 hours.

    Conclusions

    Drink sodium progressively increased fluid retention in young adults regardless of glucose or amino acids; older adults excrete urine more slowly, so a 4-hour index may suit them better.

    Limitations

    Small groups (12 per age group), healthy and hydrated at baseline, single dose of commercial products.

    Supplements Studied

    Beverage Na+ content progressively increased BHI in young adults

    Outcomes Measured

    Beverage Na+ content progressively increased BHI in young adults

    Study Details

    Year:2019
    Sample Size:24
    Quality Score:6/10

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