Mineral
    Moderate Evidence

    Electrolytes

    Electrolyte salts (sodium, potassium, chloride, citrate)

    TL;DR

    Electrolyte drinks help your body hold on to the fluid you drink, and oral rehydration solution is the standard treatment for dehydration from diarrhea. Most people don't need them day to day, and they don't prevent hyponatremia from overdrinking.

    Ideal For

    • Anyone with dehydration from diarrhea or vomiting (oral rehydration solution)
    • Older adults during illness with fluid losses
    • Athletes rehydrating after heavy sweating
    • Long or hot training sessions and events

    Avoid If

    • You have chronic kidney disease or heart failure, unless your clinician advises it
    • You take ACE inhibitors, ARBs or potassium-sparing diuretics, without checking first
    • You've been told to limit sodium or fluids
    • You're using them to drink well beyond thirst during endurance events

    Frequently Asked Questions

    Are electrolyte drinks better than water?
    Only when they contain enough sodium. Oral rehydration solution left about 300 g less urine over 4 hours than the same volume of water, while a typical sports drink was no different from water. After sweating, drinks with about 50 mmol/L sodium or more kept people in fluid balance; low-sodium drinks were largely urinated away.
    Do I need electrolytes every day?
    Most people don't. Food supplies sodium well above the 1,500 mg/day adequate intake for most adults, and US guidance is to cut back above 2,300 mg. Electrolyte products make sense during illness with fluid losses, heavy sweating or long exercise in the heat.
    Should I drink electrolytes when I have diarrhea?
    Oral rehydration solution is the standard way to treat dehydration from diarrhea, especially in children, older adults and anyone with severe watery diarrhea. It replaces losses but doesn't stop the diarrhea. For a mild bug in a healthy adult or child, water, diluted juice, soups and salty crackers are usually enough.
    Do electrolytes prevent hyponatremia in runners?
    No. In Boston Marathon runners, hyponatremia was linked to weight gain from overdrinking, and drinking sports drinks rather than water did not protect against it. The main prevention is not drinking more than you lose.
    Can electrolytes stop muscle cramps?
    The evidence is thin. One small lab study found that plain water after sweating made muscles more prone to electrically induced cramps, while an electrolyte drink did the opposite. That hasn't been confirmed for real-world cramps; see our muscle cramps page.
    Is an electrolyte drink safe if I have kidney disease?
    Check with your clinician first. With chronic kidney disease, ACE inhibitors or potassium-sparing diuretics, even modest potassium intakes can raise blood potassium to unsafe levels, and many products also carry a lot of sodium.

    Overview

    Electrolytes are the charged minerals in body fluids, chiefly sodium, potassium and chloride, that decide where water goes in the body. An electrolyte supplement is any drink, powder or tablet that adds them to water. The products range from medical oral rehydration solution (ORS), built to a World Health Organization (WHO) specification of 75 mmol/L sodium, 20 mmol/L potassium and 75 mmol/L glucose, to sports drinks and zero-sugar tablets with far less sodium.

    The strongest evidence is for ORS in dehydration caused by acute diarrhea, where Cochrane reviews have refined the formula over decades. For healthy people, controlled trials show that drinks with enough sodium are retained better than plain water: after exercise, the share of fluid the body keeps rises with the drink's sodium content, and at rest ORS left about 300 g less urine over 4 hours than the same volume of water. Typical sports drinks, with much less sodium, often perform no better than water.

    What electrolytes don't do matters as much. Salt capsules did not improve a 3-hour cycling time trial, and in marathon and ultramarathon runners hyponatremia (low blood sodium) was driven by drinking too much, not by skipping electrolytes; sports drinks did not protect against it. For mild stomach bugs in otherwise healthy people, ordinary fluids work as well as electrolyte solution.

    Most people get plenty of sodium from food already. US intake guidance is an adequate intake of 1,500 mg of sodium a day for adults, with advice to cut back if intake is above 2,300 mg, so daily high-sodium electrolyte mixes add to an intake that is usually already high. They make most sense around heavy sweating, illness with fluid losses, or in older adults at risk of dehydration.

    How It Works

    • Sodium and glucose are absorbed together in the small intestine, pulling water with them; this is the basis of oral rehydration solution.
    • Sodium in a drink keeps plasma sodium and blood volume up, which reduces the urine output that follows drinking plain water.
    • Retained sodium also sustains thirst, so people tend to keep drinking until losses are replaced.
    • Potassium replaces intracellular losses from diarrhea and vomiting; chloride and citrate help correct acid-base balance.
    • Plain water after heavy sweating dilutes blood sodium and chloride; electrolyte drinks keep them stable.

    Quick Facts

    • ORS is the standard treatment for diarrheal dehydration
    • Sodium content decides how much fluid you keep
    • Typical sports drinks often hydrate no better than water
    • Electrolytes don't prevent overdrinking hyponatremia
    • Mild stomach bugs: ordinary fluids work as well

    Supporting Research
    42 studies

    Sodium supplementation is not required to maintain serum sodium concentrations during an Ironman triathlon

    Score: 7/10
    2006
    rct

    Hew-Butler TD, Sharwood K, Collins M +2 more

    Ad libitum sodium supplementation was not necessary to preserve serum sodium concentrations

    View source

    A randomized trial to assess the potential of different beverages to affect hydration status: development of a beverage hydration index

    Score: 8/10
    2016
    rct
    n=72

    Maughan RJ, Watson P

    The mean BHI at 2 h was 1.54 ± 0.74 for the ORS

    View source

    Post-exercise rehydration in man: effects of volume consumed and drink sodium content

    Score: 5/10
    1996
    crossover
    n=12

    Shirreffs SM, Taylor AJ, Leiper JB +1 more

    both sodium concentration and fluid volume consumed interact to affect the rehydration process

    View source

    Sodium intake and post-exercise rehydration in man

    Score: 6/10
    1995
    crossover
    n=6

    Maughan RJ, Leiper JB

    the fraction of the ingested fluid that was retained was directly related to the sodium concentration

    View source

    Effect of oral rehydration solution versus spring water intake during exercise in the heat on muscle cramp susceptibility of young men

    Score: 5/10
    2021
    crossover
    n=10

    Lau WY, et al

    ORS intake during exercise decreased muscle cramp susceptibility

    View source

    Effect of Sodium Supplements and Climate on Dysnatremia During Ultramarathon Running

    Score: 5/10
    2021
    observational
    n=266

    Lipman GS, Burns P, Phillips C +4 more

    Sodium supplementation did not prevent EAH nor cause hypernatremia

    View source

    Reduced osmolarity oral rehydration solution for treating dehydration caused by acute diarrhoea in children

    Score: 9/10
    2002
    meta_analysis

    Hahn S, Kim S, Garner P

    reduced osmolarity ORS was associated with fewer unscheduled intravenous fluid infusions

    View source

    Effects of different sodium concentrations in replacement fluids during prolonged exercise in women

    Score: 5/10
    2003
    crossover
    n=13

    Twerenbold R, Knechtle B, Kakebeeke TH +4 more

    This can be minimised by the use of replacement fluids of high sodium concentration

    View source

    A randomized trial to assess beverage hydration index in healthy older adults

    Score: 6/10
    2019
    crossover
    n=24

    Clarke MM, Stanhewicz AE, Wolf ST +3 more

    Beverage Na+ content progressively increased BHI in young adults

    View source

    Effect of Dilute Apple Juice and Preferred Fluids vs Electrolyte Maintenance Solution on Treatment Failure Among Children With Mild Gastroenteritis: A Randomized Clinical Trial

    Score: 9/10
    2016
    rct
    n=647

    Freedman SB, Willan AR, Boutis K +1 more

    Its advantage in minimally dehydrated children is unproven.

    View source

    The Beverage Hydration Index: Influence of Electrolytes, Carbohydrate and Protein

    Score: 7/10
    2021
    rct

    Sollanek KJ, Kenefick RW

    Electrolyte content appears to make the largest contribution in hydration properties of beverages

    View source

    Polymer-based oral rehydration solution for treating acute watery diarrhoea

    Score: 8/10
    2016
    meta_analysis
    n=4284

    Gregorio GV, Gonzales ML, Dans LF +1 more

    Glucose-based oral rehydration solution (ORS) helps replace fluid and prevent further dehydration from acute diarrhoea

    View source

    Sodium Supplementation and Exercise-Associated Hyponatremia during Prolonged Exercise

    Score: 5/10
    2015
    observational

    Hoffman MD, Stuempfle KJ

    overhydration is the primary characteristic of those developing hyponatremia

    View source

    Sodium supplementation has no effect on endurance performance during a cycling time-trial in cool conditions: a randomised cross-over trial

    Score: 6/10
    2013
    crossover
    n=9

    Cosgrove SD, Black KE

    Sodium supplements had no effect on time-trial performance

    View source

    Hyponatremia among runners in the Boston Marathon

    Score: 7/10
    2005
    cohort
    n=488

    Almond CS, Shin AY, Fortescue EB +4 more

    female sex, composition of fluids ingested, and use of nonsteroidal antiinflammatory drugs were not

    View source

    Influence of Hydration and Electrolyte Supplementation on Incidence and Time to Onset of Exercise-Associated Muscle Cramps

    Score: 4/10
    2005
    crossover
    n=13

    Jung AP, Bishop PA, Al-Nawwas A +1 more

    carbohydrate-electrolyte beverage before and during exercise in a hot environment may delay the onset

    View source

    Increased running speed and previous cramps rather than dehydration or serum sodium changes predict exercise-associated muscle cramping: a prospective cohort study in 210 Ironman triathletes

    Score: 6/10
    2011
    cohort
    n=210

    Schwellnus MP, Drew N, Collins M

    dehydration and altered serum electrolyte balance are not causes for EAMC

    View source

    Serum electrolyte concentrations and hydration status are not associated with exercise associated muscle cramping (EAMC) in distance runners

    Score: 5/10
    2004
    cohort
    n=72

    Schwellnus MP, Nicol J, Laubscher R +1 more

    no clinically significant alterations in serum electrolyte concentrations

    View source

    Muscle Cramping During a 161-km Ultramarathon: Comparison of Characteristics of Those With and Without Cramping

    Score: 4/10
    2015
    observational
    n=280

    Hoffman MD, Stuempfle KJ

    use of sodium supplements, intake rate of sodium in supplements

    View source

    Muscle Cramping in the Marathon: Dehydration and Electrolyte Depletion vs. Muscle Damage

    Score: 4/10
    2022
    observational
    n=98

    Martínez-Navarro I, Montoya-Vieco A, Collado E +3 more

    did not exhibit a greater degree of dehydration and electrolyte depletion

    View source

    Muscle Cramping in Ultra-Trail: Dehydration and Electrolyte Depletion versus Muscle Damage

    Score: 4/10
    2026
    observational
    n=58

    Martinez-Navarro I, Vicente-Mampel J, López-Grueso R +4 more

    did not exhibit a greater degree of postrace dehydration and sodium depletion

    View source

    Sodium replacement and plasma sodium drop during exercise in the heat when fluid intake matches fluid loss

    Score: 5/10
    2009
    crossover
    n=13

    Anastasiou CA, Kavouras SA, Arnaoutis G +4 more

    sodium intake during prolonged exercise in the heat plays a significant role

    View source

    A randomized, cross-over trial assessing effects of beverage sodium concentration on plasma sodium concentration and plasma volume during prolonged exercise in the heat

    Score: 5/10
    2023
    crossover
    n=11

    Wijering LAJ, Cotter JD, Rehrer NJ

    those who fully hydrate would benefit by increased sodium content of the beverage

    View source

    Sodium-free fluid ingestion decreases plasma sodium during exercise in the heat

    Score: 4/10
    1999
    crossover
    n=10

    Vrijens DM, Rehrer NJ

    We, therefore, recommend consumption of a sodium-containing beverage to compensate for large sweat losses

    View source

    Three independent biological mechanisms cause exercise-associated hyponatremia: evidence from 2,135 weighed competitive athletic performances

    Score: 6/10
    2005
    observational
    n=2135

    Noakes TD, Sharwood K, Speedy D +4 more

    EAH can be prevented by insuring that athletes do not drink to excess during exercise

    View source

    Exercise-associated hyponatremia and hydration status in 161-km ultramarathoners

    Score: 6/10
    2013
    observational
    n=887

    Hoffman MD, Hew-Butler T, Stuempfle KJ

    excessive sodium supplementation and aggressive fluid ingestion beyond the dictates of thirst are ill advised

    View source

    Efficacy of Furosemide, Oral Sodium Chloride, and Fluid Restriction for Treatment of Syndrome of Inappropriate Antidiuresis (SIAD): An Open-label Randomized Controlled Study (The EFFUSE-FLUID Trial)

    Score: 6/10
    2020
    rct
    n=92

    Krisanapan P, Vongsanim S, Pin-On P +2 more

    furosemide with NaCl supplement in combination with fluid restriction did not show benefits

    View source

    Reflex inhibition of electrically induced muscle cramps in hypohydrated humans

    Score: 5/10
    2010
    crossover

    Miller KC, Mack GW, Knight KL +4 more

    could not be explained by rapid restoration of body fluids or electrolytes

    View source

    Risk Factors for Exercise-Associated Muscle Cramps: A Systematic Review With Meta-Analysis

    Score: 7/10
    2026
    meta_analysis
    n=11274

    Costa LDS, Correa VAF, de Oliveira VF +3 more

    The uncertainties regarding hydration status, electrolyte balance

    View source

    Reduced osmolarity oral rehydration solution for treating cholera

    Score: 8/10
    2004
    meta_analysis
    n=718

    Murphy C, Hahn S, Volmink J

    reduced osmolarity ORS is associated with biochemical hyponatremia when compared with standard ORS

    View source

    Oral Hypertonic Saline Is Effective in Reversing Acute Mild-to-Moderate Symptomatic Exercise-Associated Hyponatremia

    Score: 5/10
    2020
    rct
    n=20

    Bridges E, Altherwi T, Correa JA +1 more

    Oral HTS is effective in reversing symptoms of mild-to-moderate hyponatremia in EAH

    View source

    Serum electrolytes in Ironman triathletes with exercise-associated muscle cramping

    Score: 4/10
    2005
    observational
    n=20

    Sulzer NU, Schwellnus MP, Noakes TD

    clinically significant differences in serum electrolyte concentrations

    View source

    Impact of Nuun Electrolyte Tablets on Fluid Balance in Active Men and Women

    Score: 5/10
    2020
    crossover
    n=18

    Pence J, Bloomer RJ

    fluid balances for both concentrations more favorable compared to water

    View source

    Three percent hypohydration does not affect threshold frequency of electrically induced cramps

    Score: 5/10
    2010
    cohort
    n=10

    Miller KC, Mack GW, Knight KL +4 more

    more associated with neuromuscular fatigue than dehydration/electrolyte losses

    View source

    The Role of Electrolytes in Muscle Pain Syndromes: A Systematic Review and Meta-Analysis With Implications for Temporomandibular Disorder

    Score: 6/10
    2026
    meta_analysis

    Patil S, Falkowski A, Venkataiah VS +3 more

    Sodium-based interventions are context-specific

    View source

    Water intake after dehydration makes muscles more susceptible to cramp but electrolytes reverse that effect

    Score: 5/10
    2019
    crossover
    n=10

    Lau WY, Kato H, Nosaka K

    water intake after dehydration makes muscles more susceptible to electrical simulation-induced muscle cramp

    View source

    Electrolyte and plasma responses after pickle juice, mustard, and deionized water ingestion in dehydrated humans

    Score: 5/10
    2014
    crossover
    n=9

    Miller KC

    did not fully replenish electrolytes and fluid losses

    View source

    An intervention study of oral versus intravenous hypertonic saline administration in ultramarathon runners with exercise-associated hyponatremia: a preliminary randomized trial

    Score: 3/10
    2011
    rct
    n=8

    Rogers IR, Hook G, Stuempfle KJ +2 more

    a similar effect was not demonstrated for the same dose orally

    View source

    Case Study: Symptomatic Exercise-Associated Hyponatremia in an Endurance Runner Despite Sodium Supplementation

    Score: 2/10
    2015
    case_study

    Hoffman MD, Myers TM

    oral sodium supplementation does not necessarily prevent symptomatic EAH

    View source

    Statement of the 3rd International Exercise-Associated Hyponatremia Consensus Development Conference, Carlsbad, California, 2015

    Score: 8/10
    2015
    systematic_review

    Hew-Butler T, Rosner MH, Fowkes-Godek S

    a preventable and treatable fluid imbalance

    View source

    A randomized controlled trial of glucose versus amylase resistant starch hypo-osmolar oral rehydration solution for adult acute dehydrating diarrhea

    Score: 6/10
    2008
    rct
    n=50

    Ramakrishna BS, Subramanian V, Mohan V +4 more

    HAMS-ORS reduced diarrhea duration by 55%

    View source

    The effects of a sugar-free amino acid-containing electrolyte beverage on 5-kilometer performance, blood electrolytes, and post-exercise cramping versus a conventional carbohydrate-electrolyte sports beverage and water

    Score: 5/10
    2024
    crossover
    n=20

    McIntosh MC, Ruple BA, Kontos NJ +3 more

    favorable effects on blood electrolyte and post-exercise self-reporting cramp outcomes

    View source

    Safety Information

    Potential Side Effects

    Generally well tolerated. Strong or oversalted mixes can cause nausea or worsen diarrhea; making up powders with too little water raises their concentration. Regular high-sodium products add to total sodium intake.

    Contraindications

    Chronic kidney disease, heart failure or any condition where you have been told to restrict sodium, potassium or fluids. Severe dehydration, confusion or inability to keep fluids down need medical care rather than home rehydration.

    Drug Interactions

    • ACE inhibitors, angiotensin receptor blockers and potassium-sparing diuretics: potassium-containing products can raise blood potassium; check with your prescriber.
    • Blood pressure medicines in general: high-sodium mixes can work against sodium restriction; ask your clinician how much sodium is right for you.
    • Diuretics: change sodium and potassium handling; use electrolyte products only as your prescriber advises.

    Pregnancy & Breastfeeding

    Pregnancy: Likely safe

    Breastfeeding: Likely safe

    Dosage Guidelines

    Dosage Used in Studies

    Consult healthcare provider

    Best Time to Take

    When losses happen: during illness with diarrhea or vomiting, during long or hot exercise, and in the hours after heavy sweating.

    Best Form

    Oral rehydration solution for illness; a higher-sodium electrolyte drink or water plus food after heavy sweating.

    Bioavailability

    Sodium and glucose are absorbed together in the small intestine, which is why oral rehydration solution contains both in a set ratio.

    Dosing by Goal

    GoalDoseNotes
    Dehydration from diarrhea or vomitingOral rehydration solution made up exactly as directed (WHO formula: 75 mmol/L sodium, 75 mmol/L glucose)Sip small amounts often and keep going while losses continue; aim to keep passing urine regularly. Seek care for signs of severe dehydration.
    After exercise with heavy sweatingAbout 1.5 times the weight lost (1.5 L per kg), with a drink containing roughly 50 mmol/L sodium or more, or water with a salty mealWeigh before and after exercise to estimate losses. Lower-sodium drinks are mostly urinated away.
    During long exerciseDrink to limit weight loss to under about 2% of body weight; carbohydrate-electrolyte drinks can help in long or hot sessionsNever drink so much that you gain weight; that is what causes exercise-associated hyponatremia.
    Everyday hydrationUsually unnecessary; water and normal meals cover most peopleUS guidance: adequate intake 1,500 mg sodium a day; reduce intake if above 2,300 mg.

    Forms Compared

    Oral rehydration solution (ORS)

    Best for Dehydration from diarrhea or vomiting

    Medical formula: about 60-75 mmol/L sodium, 20 mmol/L potassium and 75-90 mmol/L glucose (reduced osmolarity, about 245 mOsm/L). Sold in pharmacies as sachets or ready-mixed.

    Sports drinks (carbohydrate-electrolyte)

    Best for Long or hot exercise sessions

    Lower sodium (often around 20 mmol/L) plus 6-8% carbohydrate. Fuel for long exercise; not adequate alone for severe diarrhea.

    Electrolyte powders and tablets

    Best for Heavy sweaters, post-exercise rehydration

    Dissolve in water; sodium ranges widely between products, so check the label. Often sugar-free.

    Salt capsules

    Best for Very long events in heat, by experienced athletes

    Sodium without fluid; used by endurance athletes. Trials show no performance benefit in cool conditions.

    Food & Timing

    Can be taken with or without food; a salty meal with water does a similar job after exercise.

    Medical Disclaimer

    The information provided on this website is for educational and informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any supplement regimen.

    Individual results may vary. The statements on this website have not been evaluated by the Food and Drug Administration. Products and information are not intended to diagnose, treat, cure, or prevent any disease.